Trimethylchlorosilane (TMCS)

CAS No.: 75-77-4
Molecular Formula: C₃H₉ClSi
Molecular Weight: 108.64 g/mol

Product Description
Trimethylchlorosilane (TMCS) is a highly reactive organosilicon compound widely used as a silylating agent, protecting reagent, and intermediate in organic and silicone chemistry. Known for its strong affinity toward hydroxyl groups, TMCS enables the efficient conversion of alcohols, acids, and phenols into their corresponding trimethylsilyl derivatives, enhancing volatility and stability—ideal for GC analysis, pharmaceutical synthesis, and fine chemical manufacturing.

Its role as a key precursor in silicone polymers, surface treatments, and hydrophobic coatings makes TMCS an essential industrial reagent. With consistent high purity and moisture-free packaging, our Trimethylchlorosilane ensures reliable performance in both laboratory and large-scale applications.

Applications

Silylating agent in organic synthesis and analytical chemistry

Essential intermediate in silicone polymer and siloxane production

Used for hydrophobic surface modification of glass, metals, and fillers

Reagent for protecting functional groups during multi-step synthesis

Enhances volatility of compounds for GC and GC-MS derivatization

Manufacturing of specialty chemicals and advanced materials

Key Features

High reactivity with hydroxyl-containing substrates

Ensures cleaner reactions and improved yields

Moisture-controlled, high-purity product

Suitable for both research and industrial manufacturing

Excellent stability under recommended storage conditions

Why Choose Our Trimethylchlorosilane?

Consistently high-purity TMCS with batch-wise quality testing

Safe, moisture-resistant and corrosion-proof packaging

Reliable supply chain with bulk and repeat order support

Competitive pricing for industrial and laboratory users

Technical assistance available for handling and application

Trusted by pharma, chemical, polymer, and R&D laboratories